See full list on PubMed here.
Escopy S, Chaikof, EL. Targeting the P-selectin/PSGL-1 pathway: Discovery of disease-modifying therapeutics for disorders of thromboinflammation. Blood Vessels, Thrombosis, and Hemostasis (Blood VTH) 2024. In press.
Eweje F, Walsh ML, Ahmad K, Ibrahim V, Alrefai A, Chen J, Chaikof EL. Protein-based nanoparticles for therapeutic nucleic acid delivery. Biomaterials 2024 Jan 2;305:122464. doi: 10.1016/j.biomaterials.2023.122464
Dhakal B, Mandhapati A, Eradi P, Park S, Fibben K, Li K, DeYong A, Escopy S, Karki G, Park DD, Haller CA, Dai E, Sun L, Lam WA, Chaikof EL. Total synthesis of a PSGL-1 glycopeptide analogue for targeted inhibition of P-selectin. J. Am. Chem. Soc. 2024. doi: 10.1021/jacs.4c05090
Pandey S, Gao XD, Krasnow NA, McElroy A, Tao YA, Duby JE, Steinbeck BJ, McCreary J, Pierce S, Tolar J, Meissner TB, Chaikof EL, Osborn MJ, Liu DR. Efficient site-specific integration of large genes in mammalian cells via continuously evolved recombinases and prime editing. Nature Biomedical Engineering In press 2024.
Mathews D, Abernethy A, Chaikof E, Charo RA, Daley GQ, Enriquez J, Gottlieb S, Kahn J, Klausner RD, Tavazoie S, Fabi R, Offodile II AC, Sherkow JS, Sullenger RD, Freiling E, Balatbat C. Regenerative Medicine: Case Study for Understanding and Anticipating Emerging Science and Technology. NAM Perspectives. Discussion Paper, National Academy of Medicine, Washington, DC. 2023. doi: 10.31478/202311d
Singhal D, Börner K, Chaikof EL, Detmar M, Hollmén M, Iliff JJ, Itkin M, Makinen T, Oliver G, Padera TP, Quardokus EM, Radtke AJ, Suami H, Weber GM, Rovira II, Muratoglu SC, Galis ZS. Mapping the lymphatic system across body scales and expertise domains: A report from the 2021 National Heart, Lung, and Blood Institute workshop at the Boston Lymphatic Symposium. Front Physiol 2023; 14:1099403.
Kudelka MR, Gu W, Matsumoto Y, Ju T, Barnes RH, Kardish RJ, Heimburg-Molinaro J, Lehoux S, Zeng J, Cohen C, Robinson BS, Shah KS, Chaikof EL, Stowell SR, Cummings RD. Targeting altered glycosylation in secreted tumor glycoproteins for broad cancer detection. Glycobiology 2023; cwad035.
Goth CK, Mehta AY, McQuillan AM, Baker KJ, Hanes MS, Park SS, Stavenhagen K, Hjortø GM, Heimburg-Molinaro J, Chaikof EL, Rosenkilde MM, Cummings RD. Chemokine binding to PSGL-1 is controlled by O-glycosylation and tyrosine sulfation. Cell Chem Biol 2023; S2451-9456(23)00191-5.
Ham HO, Xu Y, Haller CA, Dai E, Stancanelli E, Liu J, Chaikof EL. Design of an ultralow molecular weight heparin that resists heparanase biodegradation. J Med Chem 2023. doi: 10.1021/acs.jmedchem.2c02118.
Matsumoto Y, Aryal RP, Heimburg-Molinaro J, Park SS, Wever WJ, Lehoux S, Stavenhagen K, van Wijk JAE, Die IV, Chapman AB, Chaikof EL, Cummings RD. Identification and characterization of circulating immune complexes in IgA nephropathy. Sci Adv 2022; 8(43):eabm8783.
Rokosh RS, Chaikof EL. Telemedicine for screening and follow-up of abdominal aortic aneurysm Reply. J Vasc Surg 2022;75:1497–8. https://doi.org/10.1016/j.jvs.2021.12.052
Chamzas C, Eweje F, Kavraki LE, Chaikof EL. Human Health and Equity in an Age of Robotics and Intelligent Machines. NAM Perspectives. Commentary, NAM 2022. https://doi.org/10.31478/202203b
Rokosh RS, Wu WW, Schermerhorn M, Chaikof EL. Society for Vascular Surgery implementation of clinical practice guidelines for patients with an abdominal aortic aneurysm: Postoperative surveillance after abdominal aortic aneurysm repair. J Vasc Surg 2021;74:1438–9. https://doi.org/10.1016/j.jvs.2021.04.037
Panthofer AM, Olson SL, Rademacher BL, Grudzinski JK, Chaikof EL, Matsumura JS, N-TA(3)CT Investigators. Anatomic eligibility for endovascular aneurysm repair preserved over 2 years of surveillance. J Vasc Surg 2021;74:1527-1536.e1. https://doi.org/10.1016/j.jvs.2021.04.044
Varghese M, Rokosh RS, Haller CA, Chin SL, Chen J, Dai E, Xiao R, Chaikof EL, Grinstaff MW. Sulfated poly-amido-saccharides (sulPASs) are anticoagulants in vitro and in vivo. Chem Sci 2021;12:12719–25. https://doi.org/10.1039/d1sc02302k
Rokosh RS, Wu WW, Eskandari MK, Chaikof EL. Society for Vascular Surgery implementation of guidelines in abdominal aortic aneurysms: Preoperative surveillance and threshold for repair. J Vasc Surg 2021;74:1053–4. https://doi.org/10.1016/j.jvs.2021.04.068
Wong DJ, Park DD, Park SS, Haller CA, Chen J, Dai E, Liu L, Mandhapati AR, Eradi P, Dhakal B, Wever WJ, Hanes M, Sun L, Cummings RD, Chaikof EL. A PSGL-1 glycomimetic reduces thrombus burden without affecting hemostasis. Blood 2021;138:1182–93. https://doi.org/10.1182/blood.2020009428
Wong DJ, Miranda-Nieves D, Nandivada P, Patel MS, Hashimoto DA, Kent DO, Gómez-Márquez J, Lin SJ, Feldman HJ, Chaikof EL. The Surgical Program in Innovation (SPIN): A Design and Prototyping Curriculum for Surgical Trainees. Acad Med 2021;96:1306–10. https://doi.org/10.1097/ACM.0000000000003958
Ham HO, Haller CA, Su G, Dai E, Patel MS, Liu DR, Liu J, Chaikof EL. A rechargeable anti-thrombotic coating for blood-contacting devices. Biomaterials 2021;276:121011. https://doi.org/10.1016/j.biomaterials.2021.121011
Rokosh RS, Starnes BW, Chaikof EL. Society for Vascular Surgery implementation of clinical practice guidelines for patients with an abdominal aortic aneurysm: Repair of an abdominal aortic aneurysm. J Vasc Surg 2021;73:1485–7. https://doi.org/10.1016/j.jvs.2020.12.103
Chung JJ, Qiu JM, Chaikof EL, Naples JG. Multidisciplinary care initiative: A paradigm shift in the pre-clinical curriculum. Med Educ 2021;55:644. https://doi.org/10.1111/medu.14504
Park DD, Chen J, Kudelka MR, Jia N, Haller CA, Kosaraju R, Premji AM, Galizzi M, Nairn AV, Moremen KW, Cummings RD, Chaikof EL. Resident and elicited murine macrophages differ in expression of their glycomes and glycan-binding proteins. Cell Chem Biol 2021;28:567-582.e4. https://doi.org/10.1016/j.chembiol.2020.12.005
Saha K, Sontheimer EJ, Brooks PJ, Dwinell MR, Gersbach CA, Liu DR, Murray SA, Tsai SQ, Wilson RC, Anderson DG, Asokan A, Banfield JF, Bankiewicz KS, Bao G, Bulte JWM, Bursac N, Campbell JM, Carlson DF, Chaikof EL et al. The NIH Somatic Cell Genome Editing program. Nature 2021;592:195–204. https://doi.org/10.1038/s41586-021-03191-1
Rokosh RS, Mastracci TM, Chaikof EL. Society for Vascular Surgery implementation of clinical practice guidelines for patients with an abdominal aortic aneurysm: Screening for an abdominal aortic aneurysm. J Vasc Surg 2021;73:1126–7. https://doi.org/10.1016/j.jvs.2020.12.051
Tarabanis C, Miranda-Nieves D, Ferrante T, Haller CA, Chaikof EL. Standardized User-Independent Confocal Microscopy Image Acquisition and Analysis for Thickness Measurements of Microscale Collagen Scaffolds. Microsc Microanal 2021:1–6. https://doi.org/10.1017/S1431927621000234
Rokosh RS, Lewis WC, Chaikof EL, Kavraki LE. How Should We Prepare for the Post-Pandemic World of Telehealth and Digital Medicine? NAM Perspect 2021;2021:. https://doi.org/10.31478/202106a
Matsumoto Y, Kudelka MR, Hanes MS, Lehoux S, Dutta S, Jones MB, Stackhouse KA, Cervoni GE, Heimburg-Molinaro J, Smith DF, Ju T, Chaikof EL, Cummings RD. Erratum to: Identification of Tn antigen O-GalNAc-expressing glycoproteins in human carcinomas using novel anti-Tn recombinant antibodies. Glycobiology 2020;30:1015. https://doi.org/10.1093/glycob/cwaa044
Bienvenu LA, Maluenda A, McFadyen JD, Searle AK, Yu E, Haller C, Chaikof EL, Peter K, Wang X. Combined Antiplatelet/Anticoagulant Drug for Cardiac Ischemia/Reperfusion Injury. Circ Res 2020;127:1211–3. https://doi.org/10.1161/CIRCRESAHA.120.317450
Eldrup-Jorgensen J, Kraiss LW, Chaikof EL, Neal D, Forbes TL. Vascular Quality Initiative assessment of compliance with Society for Vascular Surgery clinical practice guidelines on the care of patients with abdominal aortic aneurysm. J Vasc Surg 2020;72:874–85. https://doi.org/10.1016/j.jvs.2019.10.097
Wong DJ, Chaikof EL. Inferring causality. J Vasc Surg 2020;72:387–8. https://doi.org/10.1016/j.jvs.2020.01.036
Malladi S, Miranda-Nieves D, Leng L, Grainger SJ, Tarabanis C, Nesmith AP, Kosaraju R, Haller CA, Parker KK, Chaikof EL, Günther A. Continuous Formation of Ultrathin, Strong Collagen Sheets with Tunable Anisotropy and Compaction. ACS Biomater Sci Eng 2020;6:4236–46. https://doi.org/10.1021/acsbiomaterials.0c00321
Wong DJ, Chaikof EL. The ESSEA Trial: A Clear Image of a Fuzzy Problem. Circ Cardiovasc Imaging 2020;13:e010990. https://doi.org/10.1161/CIRCIMAGING.120.010990
Wong DJ, Chaikof EL. Safety in numbers as administrative data supports the use of endovascular aneurysm repair in ruptured abdominal aortic aneurysms. J Vasc Surg 2020;71:1879–80. https://doi.org/10.1016/j.jvs.2019.07.071
Matsumoto Y, Kudelka MR, Hanes MS, Lehoux S, Dutta S, Jones MB, Stackhouse KA, Cervoni GE, Heimburg-Molinaro J, Smith DF, Ju T, Chaikof EL, Cummings RD. Identification of Tn antigen O-GalNAc-expressing glycoproteins in human carcinomas using novel anti-Tn recombinant antibodies. Glycobiology 2020;30:282–300. https://doi.org/10.1093/glycob/cwz095
McNamara SL, Brudno Y, Miller AB, Ham HO, Aizenberg M, Chaikof EL, Mooney DJ. Regenerating Antithrombotic Surfaces through Nucleic Acid Displacement. ACS Biomater Sci Eng 2020;6:2159–66. https://doi.org/10.1021/acsbiomaterials.0c00038
Castillo-Angeles M, Calvillo-Ortiz R, Barrows C, Chaikof EL, Kent TS. The Learning Environment in Surgery Clerkship: What are Faculty Perceptions? J Surg Educ 2020;77:61–8. https://doi.org/10.1016/j.jsurg.2019.07.003
Chen J, Haller CA, Jernigan FE, Koerner SK, Wong DJ, Wang Y, Cheong JE, Kosaraju R, Kwan J, Park DD, Thomas B, Bhasin S, De La Rosa RC, Premji AM, Liu L, Park E, Moss AC, Emili A, Bhasin M, Sun L, Chaikof EL. Modulation of lymphocyte-mediated tissue repair by rational design of heterocyclic aryl hydrocarbon receptor agonists. Sci Adv 2020;6:eaay8230. https://doi.org/10.1126/sciadv.aay8230
Castillo-Angeles M, Calvillo-Ortiz R, Barrows C, Chaikof EL, Kent TS. The Learning Environment in Surgery Clerkship: What are Faculty Perceptions? J Surg Educ 2020;77:61–8. https://doi.org/10.1016/j.jsurg.2019.07.003